Performance Management of 3rd Generation Partnership Project Long Term Evolution

Long Term Evolution (LTE) on 3rd Generation Partnership Project:in (3GPP) uusin, suorituskyvyltään edeltäjiään huomattavasti kehittyneempi mobiiliverkkostandardi. Verkon rakentaminen on operaattorille aina valtava investointi, jonka vuoksi operaattorit luonnollisesti haluavat maksimoida verkon tuoton samalla minimoiden sen ylläpitämisen aiheuttamat kustannukset. Verkon tuottoa voidaan parantaa optimoimalla sen suorituskykyä ja verkon ylläpitokustannuksia pienentää automatisoimalla verkonhallinnan toimintoja. Ratkaiseva vaihe verkon suorituskyvyn optimointiprosessissa on verkon suorituskyvyn arviointi. Tässä diplomityössä kuvataan LTE:n tärkeimmät verkon suorituskyvyn tunnusluvut, joiden avulla verkon toimintaa voidaan arvioida kokonaisvaltaisesti. Lisäksi diplomityössä esitellään verkonhallinnan toimintoja automatisoiva Self-Organizing-Networks (SON) -konsepti ja sen tyypilliset käyttösovellukset. Työssä arvioidaan myös näiden käyttösovellusten toteuttamiskelpoisuutta, vahvuuksia sekä heikkouksia. Diplomityön viimeisessä osassa tutkitaan järjestelmätason simulaatioiden avulla SON -konseptin Cell Outage Compensation (COC) -käyttösovellusta, jonka tavoitteena on vähentää tukiasemien vikaantumisista verkon käyttäjille aiheutuvaa haittaa. Osiossa tutkitaan tyypillisen vikaantumisen vaikutuksia, valitaan kontrolliparametrit COC -algoritmille sekä kehitetään COC -funktio. Tehdyissä simulaatioissa kehitetty COC -funktio onnistui vähentämään vikaantumisen vaikutuksia merkittävästi.Long Term Evolution (LTE) is the newest mobile network standard in the 3rd Generation Partnership Project (3GPP) evolution path, promising to considerably increase the performance of mobile networks. Building a mobile network is a huge investment for a network operator, and naturally operators try to maximize the revenue and minimize the operational expenditure created by their investment. This goal can be achieved by optimizing network performance and by minimizing the manual effort of network management. This thesis introduces the most important key performance indicators (KPI) of LTE, which can be utilized to evaluate network performance. Self-Organizing-Networks (SON) concept designed to automate many of the network management tasks is also described. Furthermore, the feasibility, advantages and disadvantages of SON use cases are evaluated. The final part of the thesis reports research carried out on the Cell Outage Compensation (COC), a SON use case designed to alleviate the effect of a network outage. The research, which was carried out using system level simulations, consisted of investigating the effects of a typical outage, selecting the most potential control parameters and developing a COC function. As a result, the developed COC function considerably alleviated the effects of the outage in the utilized simulation environmen

Contingency Games for Multi-Agent Interaction

Contingency planning, wherein an agent generates a set of possible plans conditioned on the outcome of an uncertain event, is an increasingly popular way for robots to act under uncertainty. In this work, we take a game-theoretic perspective on contingency planning which is tailored to multi-agent scenarios in which a robot's actions impact the decisions of other agents and vice versa. The resulting contingency game allows the robot to efficiently coordinate with other agents by generating strategic motion plans conditioned on multiple possible intents for other actors in the scene. Contingency games are parameterized via a scalar variable which represents a future time at which intent uncertainty will be resolved. Varying this parameter enables a designer to easily adjust how conservatively the robot behaves in the game. Interestingly, we also find that existing variants of game-theoretic planning under uncertainty are readily obtained as special cases of contingency games. Lastly, we offer an efficient method for solving N-player contingency games with nonlinear dynamics and non-convex costs and constraints. Through a series of simulated autonomous driving scenarios, we demonstrate that plans generated via contingency games provide quantitative performance gains over game-theoretic motion plans that do not account for future uncertainty reduction

After-use of peat extraction sites – A systematic review of biodiversity, climate, hydrological and social impacts

After drainage for forestry and agriculture, peat extraction is one of the most important causes of peatland degradation. When peat extraction is ceased, multiple after-use options exist, including abandonment, restoration, and replacement (e.g., forestry and agricultural use). However, there is a lack of a global synthesis of after-use research. Through a systematic review of 356 peer-reviewed scientific articles, we address this research gap and examine (1) what after-use options have been studied, (2) what the studied and recognized impacts of the after-use options are, and (3) what one can learn in terms of best practices and research gaps. The research has concentrated on the impacts of restoration (N = 162), abandonment (N = 72), and replacement (N = 94), the latter of which consists of afforestation (N = 46), cultivation (N = 34) and creation of water bodies (N = 14). The studies on abandonment, restoration, and creation of water bodies have focused mostly on analyzing vegetation and greenhouse gas (GHG) fluxes, while the studies assessing afforestation and cultivation sites mostly evaluate the provisioning ecosystem services. The studies show that active restoration measures speed-up vegetation recolonization on bare peat areas, reduce GHG emissions and decrease negative impacts on water systems. The most notable research gap is the lack of studies comparing the environmental and social impacts of the after-use options. Additionally, there is a lack of studies focusing on social impacts and downstream hydrology, as well as long-term monitoring of GHG fluxes. Based on the reviewed studies, a comparison of the impacts of the after-use options is not straightforward. We emphasize a need for comparative empirical research in the extracted sites with a broad socio-ecological and geographical context

Threatened habitat types in Finland 2018: the Baltic Sea. Red List of habitats. Part 2: Descriptions of habitat types

This report is a partial translation of the final report in Finnish on threatened habitat types (Threatened habitat types in Finland 2018, Part II: Descriptions of habitat types, The Finnish Environment 5/2018) that presents a total of 420 habitat types. This report includes all the evaluated habitat types of the Baltic Sea, as well as six new marine habitat types, which were described but not yet evaluated (NE). Also included are habitat types regarded as of least concern (LC) and those with deficient data (DD). For each habitat type a description, distribution map, photo, and the reasoning behind the assessment result are presented. The descriptions of the habitat types include their characteristics, geographical variation, connectivity to other habitat types, occurrence in Finland, reasons for being threatened and future threats, trend in the state of the habitat type, correspondence of the habitats type with habitat types covered by statutory protection, and whether the habitat type is one for which Finland has an international responsibility. Part I of the final report (in Finnish Suomen luontotyyppien uhanalaisuus 2018, SY 5/2018 and in English Threatened Habitat Types in Finland 2018, FE 2/2019) presents the assessment method for threatened habitat types, results and reasoning of the assessment, and proposals for measures prepared by the experts groups. In the whole country 186 habitats types were assessed as threatened (48% of the number of habitats types). The share of threatened habitat types is much larger in southern Finland (59%) than in northern Finland (32%). The assessment was conducted by broadly-based expert groups in 2016–2018. This was the second assessment of threatened habitat types in Finland. This assessment was conducted using the international IUCN Red List of Ecosystems method. Because of the new assessment method, the results of the first and second assessment of threatened habitat types are not directly comparable with each other. The conclusion that can be made, however, is that the decline and degradation of habitats has not diminished

MiR-185-5p regulates the development of myocardial fibrosis

Background: Cardiac fibrosis stiffens the ventricular wall, predisposes to cardiac arrhythmias and contributes to the development of heart failure. In the present study, our aim was to identify novel miRNAs that regulate the development of cardiac fibrosis and could serve as potential therapeutic targets for myocardial fibrosis. Methods and results: Analysis for cardiac samples from sudden cardiac death victims with extensive myocardial fibrosis as the primary cause of death identified dysregulation of miR-185-5p. Analysis of resident cardiac cells from mice subjected to experimental cardiac fibrosis model showed induction of miR-185-5p expression specifically in cardiac fibroblasts. In vitro, augmenting miR-185-5p induced collagen production and profibrotic activation in cardiac fibroblasts, whereas inhibition of miR-185-5p attenuated collagen production. In vivo, targeting miR-185-5p in mice abolished pressure overload induced cardiac interstitial fibrosis. Mechanistically, miR-185-5p targets apelin receptor and inhibits the anti-fibrotic effects of apelin. Finally, analysis of left ventricular tissue from patients with severe cardiomyopathy showed an increase in miR-185-5p expression together with pro-fibrotic TGF-beta 1 and collagen I. Conclusions: Our data show that miR-185-5p targets apelin receptor and promotes myocardial fibrosis.Peer reviewe

Randomised comparison of provisional side branch stenting versus a two-stent strategy for treatment of true coronary bifurcation lesions involving a large side branch:the Nordic-Baltic Bifurcation Study IV

Background - It is still uncertain whether coronary bifurcations with lesions involving a large side branch (SB) should be treated by stenting the main vessel and provisional stenting of the SB (simple) or by routine two-stent techniques (complex). We aimed to compare clinical outcome after treatment of lesions in large bifurcations by simple or complex stent implantation. Methods - The study was a randomised, superiority trial. Enrolment required a SB≥2.75 mm, ≥50% diameter stenosis in both vessels, and allowed SB lesion length up to 15 mm. The primary endpoint was a composite of cardiac death, non-procedural myocardial infarction and target lesion revascularisation at 6 months. Two-year clinical follow-up was included in this primary reporting due to lower than expected event rates. Results - A total of 450 patients were assigned to simple stenting (n=221) or complex stenting (n=229) in 14 Nordic and Baltic centres. Two-year follow-up was available in 218 (98.6%) and 228 (99.5%) patients, respectively. The primary endpoint of major adverse cardiac events (MACE) at 6 months was 5.5% vs 2.2% (risk differences 3.2%, 95% CI −0.2 to 6.8, p=0.07) and at 2 years 12.9% vs 8.4% (HR 0.63, 95% CI 0.35 to 1.13, p=0.12) after simple versus complex treatment. In the subgroup treated by newer generation drug-eluting stents, MACE was 12.0% vs 5.6% (HR 0.45, 95% CI 0.17 to 1.17, p=0.10) after simple versus complex treatment. Conclusion - In the treatment of bifurcation lesions involving a large SB with ostial stenosis, routine two-stent techniques did not improve outcome significantly compared with treatment by the simpler main vessel stenting technique after 2 years